Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina.
Common side effects when taken by mouth include nausea and itchiness. When applied to the skin, common side effects include redness and a burning sensation. In pregnancy, use on the skin or in the vagina is believed to be safe. There is no evidence of harm when used by mouth during pregnancy but this has been less well studied. When used by mouth, greater care should be taken in those with liver problems. It is in the azole class of medications and works by disrupting the fungal cell membrane.
Clotrimazole was discovered in 1969. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
In 1928 Smith & Nephew of the UK acquired the license to market and produce the Elastoplast range of bandages.
Beiersdorf bought brand rights for the Commonwealth from Smith & Nephew in 1992. It has become a genericized trademark for "sticking plaster" in some Commonwealth countries including the United Kingdom and Australia.
In some countries in Europe Hansaplast, a brand name started by Beiersdorf in 1922, is used instead. A third trademark, named Curitas, is used in parts of Latin America.
Nick Kochan wrote about Elastoplast in his book The World's Greatest Brands (1996); noting that "the early success of the brand was due to its high-stretch fabric material coupled with an effective adhesive"; and that it has as strong position in worldwide markets, particularly in the UK.
The Coors Brewing Company started as an American brewery and beer company in Golden, Colorado. In 2005, Adolph Coors Company, the holding company that owned Coors Brewing, merged with Molson, Inc. to become Molson Coors.
The first Coors brewery location in Golden, Colorado is the largest single brewing facility operating in the world.
Sparks Street is a pedestrian mall in Ottawa, Ontario, Canada. It was a main street in Ottawa that was converted into an outdoor pedestrian street in 1967, making it the earliest such street or mall in Canada.
Sparks runs from Elgin Street in the east to Bronson Avenue. The Sparks Street Mall, that contains a number of outdoor restaurants and also a number of works of art and fountains, only runs from Elgin to Bank Street. The pedestrian-only portion continues for another two blocks westward, with the final two blocks west of Lyon Street being a regular road and merges into Bronson Avenue going south.
The mall and most of the buildings on the south side are owned and operated by the National Capital Commission. Buildings on the north side of the mall were expropriated by the Government of Canada in 1973 and are currently operated by Public Works and Government Services Canada.
CHUM (1050 AM) is a Canadian radio station licensed to Toronto, Ontario. The station is owned and operated by Bell Media. CHUM's studios are co-located with TSN at 9 Channel Nine Court in the Agincourt neighborhood of Scarborough (with auxiliary studios located at 250 Richmond Street West in the Entertainment District of downtown Toronto), with its transmitter array located in the Clarkson neighborhood of Mississauga (near CFRB's own transmitter array). TSN 1050 is simulcast on Bell Satellite TV channel 989, and on Shaw Direct channel 867. The station is also carried on the 3rd HD digital subchannel of CKFM-FM
Channer’s Men’s Clothiers was formed in the fall of 1997. It previously operated under the trade name of Sammons & Channer in Westmount Shopping Centre. Channer’s moved to their present free-standing location on the corner of Wonderland and Commissioners in June 1999. In the fall of 2002, Channer’s expanded adding to their menswear and opening the ladies wear section – doubling in size and renaming to Channer’s Men’s Ladies Apparel.
CFPL first came on the air on November 28, 1953, with four hours of programming per day. That night, there was a major fire in London, on which CFPL's news program was able to report almost immediately during its first news hour. The station's transmitter was originally located atop the 500-foot (152 m) CFPL Television Tower, which was completed that year.
CFPL was the second privately-owned station in Canada (CKSO-TV in Sudbury, now CICI-TV, was the first). Its news program was the first to be scheduled at 6:00 p.m., during "the supper hour", which set the standard for other stations in Canada. In 1973, the station expanded its supper-hour news to a full hour. CFPL also later became one of the first in Canada to broadcast in color. From the day it began broadcasting, CFPL was affiliated with the Canadian Broadcasting Corporation.
CFPL was the CBC's largest private affiliate but wanted to produce and broadcast more local programming. This caused its relations with CBC to worsen over the years. CBC required affiliates like CFPL to carry a minimum amount of its schedule, and, according to station management, CBC programming was less lucrative by that time. Nonetheless, CFPL was a very successful station and posted good profits. It finally disaffiliated with CBC and went independent on September 4, 1988.
With no CBC programming, such as The National and Hockey Night in Canada to attract viewers, ratings plummeted and so did revenues. By the end of 1989, the station was almost bankrupt but tried to hang on as an independent station for another few years, even though its programming schedule did not have much beyond the news to attract viewership.
In 1992, amid poor ratings and low revenues, the station was sold to Baton Broadcasting. In 1994, the various Baton stations, including CFPL, merged to form first "Ontario Network Television", then renamed Baton Broadcast System. Baton greatly increased CFPL's news department, hiring dozens of people and rebranding the newscast as News Now. While Baton focused much of energy on news programming, it cut much non-news local programming from many stations, including CFPL.
In 1997, Baton sold CFPL and some of its other television stations to CHUM Limited. Under CHUM, CFPL joined the NewNet system and was accordingly rebranded "The New PL" in September 1998.
In February 2005, CHUM announced plans to consolidate the master control operations for CFPL, CKVR, CHRO, CHWI and CKNX at 299 Queen Street West in Toronto, and consolidating the traffic and programming departments at CFPL in London, resulting in the loss of approximately 13 staff members from CFPL. On June 3, 2005, the London master control signal came to an end, as the new consolidated master control took to air.
On August 2, 2005, CFPL was rebranded as A-Channel as part of CHUM Limited's rebranding of the NewNet stations. While Craig Media's A-Channel stations merged into Citytv following CHUM's acquisition of Craig Media in 2004. NewsNow at Noon was canceled one month earlier. On July 12, 2006, CTV owner CTVglobemedia announced plans to purchase A-Channel owner CHUM Limited with plans to divest itself of the A-Channel stations.
On June 22, 2007, all of the CHUM Limited channels (with the exception of Citytv) were officially taken over by CTVglobemedia.
On August 11, 2008, CFPL was rebranded as A as part of CTVglobemedia's rebranding of the A-Channel stations. A rebranding campaign began earlier in June 2008 with newscasts being referred to by the station's employees as A News. Following the closure of sister station, CKNX-TV in Wingham on August 31, 2009, that station became a repeater of CFPL.
On September 10, 2010, BCE announced plans to re-acquire 100% of CTVglobemedia's broadcasting arm, including CFPL, and on April 1, 2011, Bell Canada finalized its purchase of the assets of CTVglobemedia it did not already own, with CFPL (along with the rest of the A system) officially becoming part of Bell Media.
On May 30, 2011, Bell Media announced that the A television stations, including CFPL, would be rebranded as CTV Two on August 29, 2011.
Pearle Vision is an American chain of eye care stores. It is one of the largest franchised optical retailers in North America. The company was acquired by Luxottica, an Italian eyewear company, in 2004. As of December 31, 2018, Pearle Vision operated 110 corporate stores and had 419 franchises throughout North America.
LensCrafters is an international retailer of prescription eyewear and prescription sunglasses. Its stores usually host independent optometrists on-site or in an adjacent store. The company has its corporate headquarters in Mason, Ohio, a suburb of Cincinnati.
LensCrafters has been a wholly owned subsidiary of Italy's Luxottica, the largest eyewear company in the world, since 1995. At the end of 2018, Luxottica operated 1,158 LensCrafters stores, of which 1,050 are located in North America and 108 are located in China, Hong Kong and India.
